The Centers for Disease Control and Prevention (CDC) has issued aHealth Alert Network (HAN) Health Advisory to share information and notify clinicians, public health authorities, and the public about recent New World screwworm (NWS) animal cases in the Mexican state of Tamaulipas, which shares a border with the U.S. state of Texas. No NWS infestations related to this outbreak have been identified in people or animals in the United States as of January 20, 2026. However, given the potential for geographic spread, CDC is issuing this Health Advisory to increase awareness of the outbreak and to summarize CDC recommendations for clinicians and health departments in the United States on case identification and reporting, specimen collection, diagnosis, and treatment of NWS, as well as guidance for the public.